Best way to make a web interface for python script

I've made a small python script to scrap the web. I would like to make a nice and simple web interface where the user can enter data to search for and have the result displayed as a list. I understand that there's many different ways to do that but don't know which one would be the best in my case.

I would like something :

• Really simple and light
• Running locally with the less dependencies possible.

So far I've thinking about :

• A NodeJS server displaying content and executing the script
• A web framework in Python (web.py, Flask, Django..?)
• A local webserver (XAMPP) and cgi

Please note that I don't know much about web in python but I'm a bit used to NodeJS.

What would you recommend ?

Thanks, Victor