How to Persist ALL changes in web developer (F12 mode)

Is there a way to cache the changes I make when I edit remote pages.

I am using chromes native web dev toolkit but i will switch to any extension or browser to make this work.

Often times I change the loaded css/js files but am unsure how to persist the changes so that next time I visit the website its the same.

I do know how to persist css changes, but I want to be able to persist all changes to all the code that is processed locally (like the js/dom structure)