What is the guidance on concurrent calls involving HttpClient instances and its methods?

What is the difference between following "concurrent" call scenarios? Which is the preferred way and why?

Scenario 1:

Thread 1 => Create new HttpClient (C1) and invoke GetAsync to endpoint A

Thread 2 => Create new HttpClient (C2) and invoke GetAsync to endpoint A

Thread 3 => Create new HttpClient (C3) and invoke GetAsync to endpoint A

Scenario 2:

Create one HttpClient (Instance C)

Thread 1: Use C instance and invoke GetAsync to endpoint A

Thread 2: Use C instance and invoke GetAsync to endpoint A

Thread 3: Use C instance and invoke GetAsync to endpoint A

Both scenarios seem to be opening multiple connections to endpoint, except that Scenario 1 has overhead of creating and initializing multiple HttpClient instances at the beginning.