How to implement mixed mode authentication using Asp.Net Web API2 and AngularJs application?

I've a requirement of using mixed mode authentication in my projects which uses WEB API2 (Service) and AngularJs (UI) as technology stack. I've found a no of articles exploring mixed mode authentication but all were using web application. Can we implement the same via WEB API2?

Any kind of help would be appreciated.

Thank You in advance.