Is it possible to have Lync communicate with a REST API?

I have created a basic REST API where a user can ask for an acronym, and the web-page will return the meaning of the acronym via a POST call.

The majority of my end-users don't use the Internet as much as they use the Microsoft Lync application.

Is it possible for me to create a Lync account, and have it pass questions to my API, and return the answers to the user? Meaning the user just needs to open a new chat in Lync rather than a new web-page.

I'm sure this is possible, but I can't find any information on Google or on the web. How can this be accomplished?

Thanks very much.